The game is preceded by a golf tournament, Thanksgiving parade, Battle of the Bands and more.
Organizers said the event has a $30 million impact on the city of New Orleans. 50,000 to 60,000 people attend the game each year, and more than 200,000 are expected to come to town for the Bayou Classic.
The Bayou Classic will kick-off at 1:30 p.m. on Saturday and will be broadcast live on KTVE NBC 10.
Click here for a schedule of events.