Arkansas State Police say D'Angelo Mitchell was driving on Hwy 133 in Ashley County, when he ran off the left side of the highway and hit a driveway embankment.
The pickup truck went airborne and hit a large tree.
Mitchell and two others, 33-year-old Earl Turner and 44-year-old Gregory Mitchell both of Warren, AR, were also killed in the crash.
Mitchell was wearing his seat belt at the time of the crash. Troopers say the other two victims were not.